Animals Can Also Get Cancer, But Why Most Humans?

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Animals Can Also Get Cancer, But Why Most Humans?

Cancer is actually not just a human disease. Animals such as monkeys, cats and even fish can also get cancer. But in humans, the type of cancer and the possibility of outbreaks is greater than the animals. The cause is DNA mutations. Research has found that cancer can attack wild animals. For example facial tumor disease in Tasmanian Devil, fibropapillomatosis in turtles and genital carcinoma of sea lions. The cause of this cancer is also caused by human activity. However, the prevalence of cancer in humans is estimated to be higher than that of animals. A new study shows why chimpanzees that in fact are the closest cousins ​​of humans do not have as much cancer as humans. Chimps have a DNA similarity to humans about 96 percent and the 4 percent difference is already responsible for the difference in cancer rates between chimpanzees and humans. Researchers analyzing human brain and chimpanzee samples later found that certain modifications in the structure of DNA increase the risk of cancer in humans. This modification of DNA called methylation does not alter the genetic structure of DNA, but its expression alone
Our research shows that certain diseases in humans may have epigenetic origins of evolution. These findings in the long run can help develop better targeted therapies or ways to treat some human diseases, “said Soojin Yi, a researcher from the Georgia Tech School of Biology as reported by Medical Daily on Monday (27/08/2012). published in the American Journal of Human Genetics, Yi and the team collected samples from the prefrontal cortex of the human brain and chimpanzees. They then make a map of the brain’s brain changes. The result, it turns out that changes in DNA in the human brain is smaller than in chimpanzees. But researchers also found that most of the genes that undergo changes at this low level is a booster of protein binding and cell metabolism. The researchers explain this is what makes humans very susceptible to disease
These genes are strongly associated with disease, may be related to autism, abnormal sheath nerve and alcohol or other chemical dependence. This suggests that differences in gene changes between species may have a significant impact and are related to human susceptibility to certain diseases, including cancer, “Yi concluded.

(ir / ir)